14
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6541 | Ibutilide Fumarate | Corvert Fumarate,U70226E | Calcium Channel , Sodium Channel |
Ibutilide Fumarate (U70226E) is the fumarate salt form of ibutilide, a class III antiarrhythmic agent. Ibutilide exerts its effect by activating a slow, inward, predominately sodium current rather than by blocking outwar... | |||
T8491 | Vorolanib | CM082,X-82 | VEGFR , PDGFR |
Vorolanib (X-82) is an orally active VEGFR/PDGFR dual inhibitor. | |||
T3148 | MK-571 sodium | L-660711 (sodium salt),L-660711 sodium salt,Verlukast sodium,L-660711,MK571,MK-571 sodium salt,Propanoic acid | Leukotriene Receptor , LTR |
MK-571 sodium (L-660711 sodium salt) is a selective, orally active antagonist of the CysLT1 receptor. MK-571 sodium is a multidrug resistance protein-2 (ABCC2, Mrp2) inhibitor used to demonstrate the role of Mrp2 in the ... | |||
TQ0186 | Ko 143 | BCRP , ABC | |
Ko 143 is a selective inhibitor of ATP-binding cassette sub-family G member 2 (ABCG2; BCRP). | |||
T20003 | Acridone | Antibacterial , ABC | |
Acridone could induce cell apoptosis, inhibited ABCG2 (ATP-binding cassette sub-family G member 2) protein, and adjusted hormone level. | |||
T11348 | G907 | Antibiotic | |
G907 is a selective and potent antagonist of the small molecule ATP-binding cassette (ABC) transporter protein MsbA, with bactericidal activity, which traps MsbA in the inner lipopolysaccharide. G907 inhibits E. coli Msb... | |||
T2024 | A-803467 | A 803467,A803467 | Sodium Channel |
A-803467 is a selective NaV1.8 channel blocker. | |||
T32085 | HM30181AK | HM-30181AK,HM 30181AK | |
HM30181AK is an inhibitor of the adenosine triphosphate (ATP) binding cassette (ABC) transporter P-glycoprotein (P-gp) with adjuvant activity. | |||
T16107 | ML230 | CID44640177,SID 88095709 | CGRP Receptor |
ML230 is a selective ATP-binding cassette (ABC) transporter ABCG2 inhibitor. It 36-fold selective for ABCG2 over ABCB1 (EC50s: 0.13 μM and 4.65 μM, respectively). | |||
T13222 | TTT-28 | Others | |
TTT-28 is a thiazole-valine peptidomimetic, and is a selective ABCB1 (P-gp/MDR1) inhibitor with high efficacy and low toxicity, which reverses the ATP-binding cassette sub-family B member 1 (ABCB1)-mediated Multidrug res... | |||
T36485 | Becatecarin | ||
Becatecarin is a water-soluble, diethylaminoethyl analog of the antineoplastic antibiotic rebeccamycin. It intercalates into DNA, stabilizing the DNA-topoisomerase complex. This results in the potent catalytic inhibition... | |||
T73935 | MsbA-IN-6 | Antibiotic | |
MsbA-IN-6 is a potent antibiotic and inhibitor of the gram-negative ATP-binding cassette (ABC) transporter MsbA, an essential protein required for transporting lipopolysaccharide across the inner bacterial membrane. It e... | |||
T35696 | Olomoucine II | ||
Olomoucine II is an inhibitor of cyclin-dependent kinases (CDKs; IC50s = 7.6, 0.1, 19.8, 0.45, and 0.06 μM for Cdk1, -2, -4, -7, and -9, respectively).1It is selective for CDKs over 10 additional kinases (IC50s = >100 μM... | |||
T83683 | St-Ht31 ammonium | sHt31 | |
st-Ht31, a cell-permeable stearated peptide derived from the amphipathic helix domain of A-kinase anchoring proteins (AKAPs), effectively binds protein kinase A (PKA), impacting PKA's cellular interactions without alteri... |